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A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis
[Image: see text] Discovering compounds and mechanisms for inhibiting ferroptosis, a form of regulated, nonapoptotic cell death, has been of great interest in recent years. In this study, we demonstrate the ability of XJB-5-131, JP4-039, and other nitroxide-based lipid peroxidation mitigators to pre...
Autores principales: | Krainz, Tanja, Gaschler, Michael M., Lim, Chaemin, Sacher, Joshua R., Stockwell, Brent R., Wipf, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043442/ https://www.ncbi.nlm.nih.gov/pubmed/27725964 http://dx.doi.org/10.1021/acscentsci.6b00199 |
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