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The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs
Once every menstrual cycle, eggs are ovulated into the oviduct where they await fertilization. The ovulated eggs are arrested in metaphase of the second meiotic division, and only complete meiosis upon fertilization. It is crucial that the maintenance of metaphase arrest is tightly controlled, becau...
Autores principales: | Pasternak, Michał, Pfender, Sybille, Santhanam, Balaji, Schuh, Melina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043581/ https://www.ncbi.nlm.nih.gov/pubmed/27605379 http://dx.doi.org/10.1098/rsob.160184 |
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