Single-cell RNA sequencing reveals dynamic changes in A-to-I RNA editome during early human embryogenesis

BACKGROUND: A-to-I RNA-editing mediated by ADAR (adenosine deaminase acting on RNA) enzymes that converts adenosine to inosine in RNA sequence can generate mutations and alter gene regulation in metazoans. Previous studies have shown that A-to-I RNA-editing plays vital roles in mouse embryogenesis....

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Detalles Bibliográficos
Autores principales: Qiu, Si, Li, Wenhui, Xiong, Heng, Liu, Dongbing, Bai, Yali, Wu, Kui, Zhang, Xiuqing, Yang, Huanming, Ma, Kun, Hou, Yong, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://www.ncbi.nlm.nih.gov/pubmed/27687780
http://dx.doi.org/10.1186/s12864-016-3115-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043600/
https://www.ncbi.nlm.nih.gov/pubmed/27687780
http://dx.doi.org/10.1186/s12864-016-3115-2

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