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Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study
BACKGROUND: Patients with lower extremity peripheral artery disease (PAD) have decreased mobility, which is not fully explained by impaired blood supply to the lower limb. Additionally, reports are conflicted regarding fiber type distribution patterns in PAD, but agree that skeletal muscle mitochond...
Autores principales: | White, Sarah H., McDermott, Mary M., Sufit, Robert L., Kosmac, Kate, Bugg, Alex W., Gonzalez-Freire, Marta, Ferrucci, Luigi, Tian, Lu, Zhao, Lihui, Gao, Ying, Kibbe, Melina R., Criqui, Michael H., Leeuwenburgh, Christiaan, Peterson, Charlotte A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043620/ https://www.ncbi.nlm.nih.gov/pubmed/27687713 http://dx.doi.org/10.1186/s12967-016-1030-6 |
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