Fluoxetine Inhibits NLRP3 Inflammasome Activation: Implication in Depression

BACKGROUND: Emerging evidence indicates that NLRP3 inflammasome-induced inflammation plays a crucial role in the pathogenesis of depression. Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the treatment of depression. Fluoxetine, a widely used antidepressant, has...

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Detalles Bibliográficos
Autores principales: Du, Ren-Hong, Tan, Jun, Sun, Xi-Yang, Lu, Ming, Ding, Jian-Hua, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043644/
https://www.ncbi.nlm.nih.gov/pubmed/27207922
http://dx.doi.org/10.1093/ijnp/pyw037

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