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Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis
PURPOSE: Intensive Care Unit (ICU)-acquired hypernatremia (IAH) is a serious electrolyte disturbance that recently was shown to present an independent risk factor for mortality in critically ill patients. IAH has not been widely investigated in Surgical ICU (SICU) patients. No study has specifically...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044724/ https://www.ncbi.nlm.nih.gov/pubmed/27833483 http://dx.doi.org/10.4103/1658-354X.177327 |
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author | Alansari, Mariam A. Abdulmomen, Ahmed Hussein, Mohammed Zubaidi, Ahmad Mohmmad Alswaiti, Jalal T. |
author_facet | Alansari, Mariam A. Abdulmomen, Ahmed Hussein, Mohammed Zubaidi, Ahmad Mohmmad Alswaiti, Jalal T. |
author_sort | Alansari, Mariam A. |
collection | PubMed |
description | PURPOSE: Intensive Care Unit (ICU)-acquired hypernatremia (IAH) is a serious electrolyte disturbance that recently was shown to present an independent risk factor for mortality in critically ill patients. IAH has not been widely investigated in Surgical ICU (SICU) patients. No study has specifically investigated IAH epidemiology in the Kingdome of Saudi Arabia (KSA) in general SICU. The objectives of this study are to assess the epidemiological characteristics and prognostic impact of IAH on SICU mortality and outcome in KSA and compare it with international figures. MATERIALS AND METHODS: A retrospective observational study on a prospectively collected data of patients (14 years of age or older) admitted to SICU over 2 years, with normal serum sodium on admission and who developed IAH (serum sodium above 145 mmol/L) from day two of admission. Traumatic brain injury patients with therapeutic target sodium level above 145 mmol/L were excluded. RESULTS: Over 2 years study period, 864 patients were admitted to SICU. A total of 50 (5.8%) developed IAH and were included in the study. Twenty-eight (56%) patients were male. The median age was 47 (14-84) years. The mean (± standard deviation) Acute Physiology and Chronic Health Evaluation II score was 17 ± 6.5. The incident density (the rate of occurrence of IAH per 100 days care for SICU admission for the first episode) was 0.71. Risk factors include mechanical ventilation, male sex, age ≥50 years, postgastrointestinal surgeries, weekend and night admission. SICU mortality was 40%. The SICU and hospital median (range) length of stay was 8.3 (2-53) and 28.8 (3-95), respectively. CONCLUSIONS: IAH is not uncommon in SICU patients and is associated with increased risk of SICU as well as hospital mortality. |
format | Online Article Text |
id | pubmed-5044724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-50447242016-11-11 Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis Alansari, Mariam A. Abdulmomen, Ahmed Hussein, Mohammed Zubaidi, Ahmad Mohmmad Alswaiti, Jalal T. Saudi J Anaesth Original Article PURPOSE: Intensive Care Unit (ICU)-acquired hypernatremia (IAH) is a serious electrolyte disturbance that recently was shown to present an independent risk factor for mortality in critically ill patients. IAH has not been widely investigated in Surgical ICU (SICU) patients. No study has specifically investigated IAH epidemiology in the Kingdome of Saudi Arabia (KSA) in general SICU. The objectives of this study are to assess the epidemiological characteristics and prognostic impact of IAH on SICU mortality and outcome in KSA and compare it with international figures. MATERIALS AND METHODS: A retrospective observational study on a prospectively collected data of patients (14 years of age or older) admitted to SICU over 2 years, with normal serum sodium on admission and who developed IAH (serum sodium above 145 mmol/L) from day two of admission. Traumatic brain injury patients with therapeutic target sodium level above 145 mmol/L were excluded. RESULTS: Over 2 years study period, 864 patients were admitted to SICU. A total of 50 (5.8%) developed IAH and were included in the study. Twenty-eight (56%) patients were male. The median age was 47 (14-84) years. The mean (± standard deviation) Acute Physiology and Chronic Health Evaluation II score was 17 ± 6.5. The incident density (the rate of occurrence of IAH per 100 days care for SICU admission for the first episode) was 0.71. Risk factors include mechanical ventilation, male sex, age ≥50 years, postgastrointestinal surgeries, weekend and night admission. SICU mortality was 40%. The SICU and hospital median (range) length of stay was 8.3 (2-53) and 28.8 (3-95), respectively. CONCLUSIONS: IAH is not uncommon in SICU patients and is associated with increased risk of SICU as well as hospital mortality. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5044724/ /pubmed/27833483 http://dx.doi.org/10.4103/1658-354X.177327 Text en Copyright: © Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Alansari, Mariam A. Abdulmomen, Ahmed Hussein, Mohammed Zubaidi, Ahmad Mohmmad Alswaiti, Jalal T. Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title | Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title_full | Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title_fullStr | Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title_full_unstemmed | Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title_short | Acquired hypernatremia in a general surgical Intensive Care Unit: Incidence and prognosis |
title_sort | acquired hypernatremia in a general surgical intensive care unit: incidence and prognosis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044724/ https://www.ncbi.nlm.nih.gov/pubmed/27833483 http://dx.doi.org/10.4103/1658-354X.177327 |
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