Role of the B Allele of Influenza A Virus Segment 8 in Setting Mammalian Host Range and Pathogenicity

Two alleles of segment 8 (NS) circulate in nonchiropteran influenza A viruses. The A allele is found in avian and mammalian viruses, but the B allele is viewed as being almost exclusively found in avian viruses. This might reflect the fact that one or both of its encoded proteins (NS1 and NEP) are m...

Descripción completa

Detalles Bibliográficos
Autores principales: Turnbull, Matthew L., Wise, Helen M., Nicol, Marlynne Q., Smith, Nikki, Dunfee, Rebecca L., Beard, Philippa M., Jagger, Brett W., Ligertwood, Yvonne, Hardisty, Gareth R., Xiao, Haixia, Benton, Donald J., Coburn, Alice M., Paulo, Joao A., Gygi, Steven P., McCauley, John W., Taubenberger, Jeffery K., Lycett, Samantha J., Weekes, Michael P., Dutia, Bernadette M., Digard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044859/
https://www.ncbi.nlm.nih.gov/pubmed/27489273
http://dx.doi.org/10.1128/JVI.01205-16

Ejemplares similares

Ejemplares similares