Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart

The Drosophila cardiac tube was once thought to be a simple linear structure, however research over the past 15 years has revealed significant cellular and molecular complexity to this organ. Prior reviews have focused upon the gene regulatory networks responsible for the specification of the cardia...

Descripción completa

Detalles Bibliográficos
Autores principales: Lovato, TyAnna L., Cripps, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044875/
https://www.ncbi.nlm.nih.gov/pubmed/27695700
http://dx.doi.org/10.3390/jcdd3020018
_version_ 1782457010185306112
author Lovato, TyAnna L.
Cripps, Richard M.
author_facet Lovato, TyAnna L.
Cripps, Richard M.
author_sort Lovato, TyAnna L.
collection PubMed
description The Drosophila cardiac tube was once thought to be a simple linear structure, however research over the past 15 years has revealed significant cellular and molecular complexity to this organ. Prior reviews have focused upon the gene regulatory networks responsible for the specification of the cardiac field and the activation of cardiac muscle structural genes. Here we focus upon highlighting the existence, function, and development of unique cell types within the dorsal vessel, and discuss their correspondence to analogous structures in the vertebrate heart.
format Online
Article
Text
id pubmed-5044875
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-50448752016-09-30 Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart Lovato, TyAnna L. Cripps, Richard M. J Cardiovasc Dev Dis Review The Drosophila cardiac tube was once thought to be a simple linear structure, however research over the past 15 years has revealed significant cellular and molecular complexity to this organ. Prior reviews have focused upon the gene regulatory networks responsible for the specification of the cardiac field and the activation of cardiac muscle structural genes. Here we focus upon highlighting the existence, function, and development of unique cell types within the dorsal vessel, and discuss their correspondence to analogous structures in the vertebrate heart. MDPI 2016-05-12 /pmc/articles/PMC5044875/ /pubmed/27695700 http://dx.doi.org/10.3390/jcdd3020018 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lovato, TyAnna L.
Cripps, Richard M.
Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title_full Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title_fullStr Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title_full_unstemmed Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title_short Regulatory Networks that Direct the Development of Specialized Cell Types in the Drosophila Heart
title_sort regulatory networks that direct the development of specialized cell types in the drosophila heart
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044875/
https://www.ncbi.nlm.nih.gov/pubmed/27695700
http://dx.doi.org/10.3390/jcdd3020018
work_keys_str_mv AT lovatotyannal regulatorynetworksthatdirectthedevelopmentofspecializedcelltypesinthedrosophilaheart
AT crippsrichardm regulatorynetworksthatdirectthedevelopmentofspecializedcelltypesinthedrosophilaheart

Ejemplares similares