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Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months aft...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044921/ https://www.ncbi.nlm.nih.gov/pubmed/27661051 http://dx.doi.org/10.1097/MD.0000000000004942 |
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author | Shan, Jinlan Zhang, Shizhen Wang, Zhen Fu, Yanbiao Li, Ling Wang, Xiaochen |
author_facet | Shan, Jinlan Zhang, Shizhen Wang, Zhen Fu, Yanbiao Li, Ling Wang, Xiaochen |
author_sort | Shan, Jinlan |
collection | PubMed |
description | BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months after first diagnosis, presenting a huge pelvic mass (14 cm × 11 cm) by CT scan. Histopathological examination has demonstrated a metastatic phyllodes tumor. After postoperative chemotherapy treatment, a longer survival has been achieved, which is more than 72 months. RESULTS: Our case report describes a breast PT with several local recurrences and a rare metastasis (pelvic cavity), but long-term overall survival was achieved after surgery and chemotherapy. CONCLUSION: We conclude that trustworthy prognosticators that identify patients with excessive potential of aggressive clinical course should be explored. Moreover, proper treatment could prolong overall survival of metastatic PT patients. |
format | Online Article Text |
id | pubmed-5044921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-50449212016-10-06 Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review Shan, Jinlan Zhang, Shizhen Wang, Zhen Fu, Yanbiao Li, Ling Wang, Xiaochen Medicine (Baltimore) 5700 BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months after first diagnosis, presenting a huge pelvic mass (14 cm × 11 cm) by CT scan. Histopathological examination has demonstrated a metastatic phyllodes tumor. After postoperative chemotherapy treatment, a longer survival has been achieved, which is more than 72 months. RESULTS: Our case report describes a breast PT with several local recurrences and a rare metastasis (pelvic cavity), but long-term overall survival was achieved after surgery and chemotherapy. CONCLUSION: We conclude that trustworthy prognosticators that identify patients with excessive potential of aggressive clinical course should be explored. Moreover, proper treatment could prolong overall survival of metastatic PT patients. Wolters Kluwer Health 2016-09-23 /pmc/articles/PMC5044921/ /pubmed/27661051 http://dx.doi.org/10.1097/MD.0000000000004942 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 5700 Shan, Jinlan Zhang, Shizhen Wang, Zhen Fu, Yanbiao Li, Ling Wang, Xiaochen Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title | Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title_full | Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title_fullStr | Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title_full_unstemmed | Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title_short | Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review |
title_sort | breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: a case report and literature review |
topic | 5700 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044921/ https://www.ncbi.nlm.nih.gov/pubmed/27661051 http://dx.doi.org/10.1097/MD.0000000000004942 |
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