Cargando…

Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review

BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months aft...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Jinlan, Zhang, Shizhen, Wang, Zhen, Fu, Yanbiao, Li, Ling, Wang, Xiaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044921/
https://www.ncbi.nlm.nih.gov/pubmed/27661051
http://dx.doi.org/10.1097/MD.0000000000004942
_version_ 1782457019890925568
author Shan, Jinlan
Zhang, Shizhen
Wang, Zhen
Fu, Yanbiao
Li, Ling
Wang, Xiaochen
author_facet Shan, Jinlan
Zhang, Shizhen
Wang, Zhen
Fu, Yanbiao
Li, Ling
Wang, Xiaochen
author_sort Shan, Jinlan
collection PubMed
description BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months after first diagnosis, presenting a huge pelvic mass (14 cm × 11 cm) by CT scan. Histopathological examination has demonstrated a metastatic phyllodes tumor. After postoperative chemotherapy treatment, a longer survival has been achieved, which is more than 72 months. RESULTS: Our case report describes a breast PT with several local recurrences and a rare metastasis (pelvic cavity), but long-term overall survival was achieved after surgery and chemotherapy. CONCLUSION: We conclude that trustworthy prognosticators that identify patients with excessive potential of aggressive clinical course should be explored. Moreover, proper treatment could prolong overall survival of metastatic PT patients.
format Online
Article
Text
id pubmed-5044921
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-50449212016-10-06 Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review Shan, Jinlan Zhang, Shizhen Wang, Zhen Fu, Yanbiao Li, Ling Wang, Xiaochen Medicine (Baltimore) 5700 BACKGROUND: Malignant phyllodes tumor (PT) is a rare fibro epithelial neoplasm of the breast, which is poor prognosis due to high risk of recurrence and distant metastasis. METHODS: We report a case of malignant PT. It had recurred locally five times, and the sixth relapse was occurred 54 months after first diagnosis, presenting a huge pelvic mass (14 cm × 11 cm) by CT scan. Histopathological examination has demonstrated a metastatic phyllodes tumor. After postoperative chemotherapy treatment, a longer survival has been achieved, which is more than 72 months. RESULTS: Our case report describes a breast PT with several local recurrences and a rare metastasis (pelvic cavity), but long-term overall survival was achieved after surgery and chemotherapy. CONCLUSION: We conclude that trustworthy prognosticators that identify patients with excessive potential of aggressive clinical course should be explored. Moreover, proper treatment could prolong overall survival of metastatic PT patients. Wolters Kluwer Health 2016-09-23 /pmc/articles/PMC5044921/ /pubmed/27661051 http://dx.doi.org/10.1097/MD.0000000000004942 Text en Copyright © 2016 the Author(s). Published by Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle 5700
Shan, Jinlan
Zhang, Shizhen
Wang, Zhen
Fu, Yanbiao
Li, Ling
Wang, Xiaochen
Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title_full Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title_fullStr Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title_full_unstemmed Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title_short Breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: A case report and literature review
title_sort breast malignant phyllodes tumor with rare pelvic metastases and long-term overall survival: a case report and literature review
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044921/
https://www.ncbi.nlm.nih.gov/pubmed/27661051
http://dx.doi.org/10.1097/MD.0000000000004942
work_keys_str_mv AT shanjinlan breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview
AT zhangshizhen breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview
AT wangzhen breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview
AT fuyanbiao breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview
AT liling breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview
AT wangxiaochen breastmalignantphyllodestumorwithrarepelvicmetastasesandlongtermoverallsurvivalacasereportandliteraturereview