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A novel Nrf2 activator from microbial transformation inhibits radiation-induced dermatitis in mice

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcriptional factor that regulates many antioxidants, and we have recently succeeded in obtaining a novel Nrf2 activator, RS9, from microbial transformation. RS9 is categorized as a triterpenoid, and well-known triterpenoids such as RTA 402...

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Detalles Bibliográficos
Autores principales: Nakagami, Yasuhiro, Masuda, Kayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045074/
https://www.ncbi.nlm.nih.gov/pubmed/27242339
http://dx.doi.org/10.1093/jrr/rrw039