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Anakinra and related drugs targeting interleukin-1 in the treatment of cryopyrin-associated periodic syndromes
Anakinra is an interleukin (IL) receptor antagonist that works by blocking the biological activity of IL-1 by competitively inhibiting binding of IL-1 to the type 1 interleukin receptor. IL-1 production is induced in response to inflammatory stimuli and mediates various physiological mechanisms, inc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045113/ https://www.ncbi.nlm.nih.gov/pubmed/27790031 http://dx.doi.org/10.2147/OARRR.S46017 |