Bone Morphogenetic Protein-7 Antagonizes Myocardial Fibrosis Induced by Atrial Fibrillation by Restraining Transforming Growth Factor-β (TGF-β)/Smads Signaling

BACKGROUND: This aim of this study was to investigate the expression of BMP-7 in atrial fibrillation and illuminate the role of BMP-7 and TGF-β/Smads signaling in myocardial fibrosis. MATERIAL/METHODS: Fibrosis of myocardial fibroblasts was induced by TGF-β1 and the optimal condition was determined...

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Detalles Bibliográficos
Autores principales: Chen, Xinjun, Xu, Jing, Jiang, Baozhou, Liu, Danping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045133/
https://www.ncbi.nlm.nih.gov/pubmed/27677228
http://dx.doi.org/10.12659/MSM.897560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045133/
https://www.ncbi.nlm.nih.gov/pubmed/27677228
http://dx.doi.org/10.12659/MSM.897560

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