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STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function

Mammalian CST (CTC1-STN1-TEN1) participates in multiple aspects of telomere replication and genome-wide recovery from replication stress. CST resembles Replication Protein A (RPA) in that it binds ssDNA and STN1 and TEN1 are structurally similar to RPA2 and RPA3. Conservation between CTC1 and RPA1 i...

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Detalles Bibliográficos
Autores principales:	Bhattacharjee, Anukana, Stewart, Jason, Chaiken, Mary, Price, Carolyn M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045167/ https://www.ncbi.nlm.nih.gov/pubmed/27690379 http://dx.doi.org/10.1371/journal.pgen.1006342

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