A Novel Entry/Uncoating Assay Reveals the Presence of at Least Two Species of Viral Capsids During Synchronized HIV-1 Infection

To better characterize the behavior of HIV-1 capsids we developed EURT, for Entry/Uncoating assay based on core-packaged RNA availability and Translation. EURT is an alternative to Blam-Vpr, but as reporter RNA translation relies on core opening, it can be used to study viral capsids behavior. Our s...

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Detalles Bibliográficos
Autores principales: Da Silva Santos, Claire, Tartour, Kevin, Cimarelli, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045187/
https://www.ncbi.nlm.nih.gov/pubmed/27690375
http://dx.doi.org/10.1371/journal.ppat.1005897

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