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High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC
The Staphylococcus aureus manganese transporter protein MntC is under investigation as a component of a prophylactic S.aureus vaccine. Passive immunization with monoclonal antibodies mAB 305-78-7 and mAB 305-101-8 produced using MntC was shown to significantly reduce S. aureus burden in an infant ra...
Autores principales: | Gribenko, Alexey V., Parris, Kevin, Mosyak, Lidia, Li, Sheng, Handke, Luke, Hawkins, Julio C., Severina, Elena, Matsuka, Yury V., Anderson, Annaliesa S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045189/ https://www.ncbi.nlm.nih.gov/pubmed/27689696 http://dx.doi.org/10.1371/journal.ppat.1005908 |
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