Widespread Shortening of 3’ Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

The contribution of pre-mRNA processing mechanisms to the regulation of immune responses remains poorly studied despite emerging examples of their role as regulators of immune defenses. We sought to investigate the role of mRNA processing in the cellular responses of human macrophages to live bacter...

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Detalles Bibliográficos
Autores principales: Pai, Athma A., Baharian, Golshid, Pagé Sabourin, Ariane, Brinkworth, Jessica F., Nédélec, Yohann, Foley, Joseph W., Grenier, Jean-Christophe, Siddle, Katherine J., Dumaine, Anne, Yotova, Vania, Johnson, Zachary P., Lanford, Robert E., Burge, Christopher B., Barreiro, Luis B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045211/
https://www.ncbi.nlm.nih.gov/pubmed/27690314
http://dx.doi.org/10.1371/journal.pgen.1006338

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