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Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using Xenopus we show that Cp110 inhibits cilia formation at high le...
Autores principales: | Walentek, Peter, Quigley, Ian K, Sun, Dingyuan I, Sajjan, Umeet K, Kintner, Christopher, Harland, Richard M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045295/ https://www.ncbi.nlm.nih.gov/pubmed/27623009 http://dx.doi.org/10.7554/eLife.17557 |
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