Cargando…

Mutations of SETBP1 and JAK3 in juvenile myelomonocytic leukemia: a report from the Italian AIEOP study group

Juvenile myelomonocytic leukemia (JMML) is a rare aggressive disease of early childhood. Driver mutations in the Ras signaling pathways are a key feature of JMML patients. Mutations in SETBP1 and JAK3 were recently identified in a subset of JMML patients characterized by poor prognosis and progressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bresolin, Silvia, De Filippi, Paola, Vendemini, Francesca, D'Alia, Mirko, Zecca, Marco, Meyer, Lueder H., Danesino, Cesare, Locatelli, Franco, Masetti, Riccardo, Basso, Giuseppe, te Kronnie, Geertruy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045366/
https://www.ncbi.nlm.nih.gov/pubmed/26980750
http://dx.doi.org/10.18632/oncotarget.8016