Integrative transcriptome analysis identifies deregulated microRNA-transcription factor networks in lung adenocarcinoma

Herein, we aimed at identifying global transcriptome microRNA (miRNA) changes and miRNA target genes in lung adenocarcinoma. Samples were selected as training (N = 24) and independent validation (N = 34) sets. Tissues were microdissected to obtain >90% tumor or normal lung cells, subjected to miR...

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Detalles Bibliográficos
Autores principales: Cinegaglia, Naiara C., Andrade, Sonia Cristina S., Tokar, Tomas, Pinheiro, Maísa, Severino, Fábio E., Oliveira, Rogério A., Hasimoto, Erica N., Cataneo, Daniele C., Cataneo, Antônio J.M., Defaveri, Júlio, Souza, Cristiano P., Marques, Márcia M.C., Carvalho, Robson F., Coutinho, Luiz L., Gross, Jefferson L., Rogatto, Silvia R., Lam, Wan L., Jurisica, Igor, Reis, Patricia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045367/
https://www.ncbi.nlm.nih.gov/pubmed/27081085
http://dx.doi.org/10.18632/oncotarget.8713

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