Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cells

The cinobufagin (CB) has a broad spectrum of cytotoxicity to inhibit cell proliferation of various human cancer cell lines, but the molecular mechanisms still remain elusive. Here we observed that CB inhibited the cell proliferation and tumor growth, but induced cell cycle arrest and apoptosis in a...

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Detalles Bibliográficos
Autores principales: Zhang, Guangxin, Wang, Chao, Sun, Mei, Li, Jindong, Wang, Bin, Jin, Chengyan, Hua, Peiyan, Song, Ge, Zhang, Yifan, Nguyen, Lisa L.H., Cui, Ranji, Liu, Runhua, Wang, Lizhong, Zhang, Xingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045368/
https://www.ncbi.nlm.nih.gov/pubmed/26959116
http://dx.doi.org/10.18632/oncotarget.7898

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