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Chemotherapy-induced uridine diphosphate release promotes breast cancer metastasis through P2Y(6) activation

Although purinergic signaling is important in regulation of immune responses, the therapeutic potential of it in the tumor microenvironment is little defined. In this study, we demonstrate that UDP/P2Y(6) signaling facilitates breast cancer metastasis both in vitro and in vivo. We found that P2Y(6)...

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Detalles Bibliográficos
Autores principales:	Ma, Xiaobin, Pan, Xinhua, Wei, Yinglei, Tan, Binhe, Yang, Linli, Ren, Hua, Qian, Min, Du, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045376/ https://www.ncbi.nlm.nih.gov/pubmed/27074554 http://dx.doi.org/10.18632/oncotarget.8664

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