Cargando…

Mitochondrial DNA content in breast cancer: Impact on in vitro and in vivo phenotype and patient prognosis

Reduced mitochondrial DNA (mtDNA) content in breast cancer cell lines has been associated with transition towards a mesenchymal phenotype, but its clinical consequences concerning breast cancer dissemination remain unidentified. Here, we aimed to clarify the link between mtDNA content and a mesenchy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weerts, Marjolein J.A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Foekens, John A., Sleijfer, Stefan, Martens, John W.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045386/ https://www.ncbi.nlm.nih.gov/pubmed/27081694 http://dx.doi.org/10.18632/oncotarget.8688

Ejemplares similares

High TWIST1 mRNA expression is associated with poor prognosis in lymph node-negative and estrogen receptor-positive human breast cancer and is co-expressed with stromal as well as ECM related genes
por: Riaz, Muhammad, et al.
Publicado: (2012)

Mitochondrial RNA Expression and Single Nucleotide Variants in Association with Clinical Parameters in Primary Breast Cancers
por: Weerts, Marjolein J. A., et al.
Publicado: (2018)

Distinct inherited metastasis susceptibility exists for different breast cancer subtypes: a prognosis study
por: Hsieh, Szu-Min, et al.
Publicado: (2009)

Pathway analysis of gene signatures predicting metastasis of node-negative primary breast cancer
por: Yu, Jack X, et al.
Publicado: (2007)

Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study
por: Sieuwerts, Anieta M, et al.
Publicado: (2010)

The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer
por: Liu, Jingjing, et al.
Publicado: (2016)

Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer
por: De Marchi, Tommaso, et al.
Publicado: (2017)

Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells
por: Sieuwerts, Anieta M., et al.
Publicado: (2009)

A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds
por: Mustafa, Dana A. M., et al.
Publicado: (2015)

Tumor-Specific Mitochondrial DNA Variants Are Rarely Detected in Cell-Free DNA()()
por: Weerts, M.J.A., et al.
Publicado: (2018)

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor()
por: Beije, Nick, et al.
Publicado: (2016)

Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1(st)-line tamoxifen therapy in breast cancer
por: Uhr, K., et al.
Publicado: (2018)

Comparative Proteome Analysis Revealing an 11-Protein Signature for Aggressive Triple-Negative Breast Cancer
por: Liu, Ning Qing, et al.
Publicado: (2014)

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells
por: Ansems, Marleen, et al.
Publicado: (2015)

Correction: MicroRNA expression in pre-treatment plasma of patients with benign breast diseases and breast cancer
por: Lagendijk, Mirelle, et al.
Publicado: (2018)

MicroRNA expression in pre-treatment plasma of patients with benign breast diseases and breast cancer
por: Lagendijk, Mirelle, et al.
Publicado: (2018)

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations
por: Redis, Roxana S, et al.
Publicado: (2013)

Molecular characteristics of circulating tumor cells resemble the liver metastasis more closely than the primary tumor in metastatic colorectal cancer
por: Onstenk, Wendy, et al.
Publicado: (2016)

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen
por: M. Sieuwerts, Anieta, et al.
Publicado: (2020)

Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers
por: Sieuwerts, Anieta M., et al.
Publicado: (2014)

The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer
por: Vitale, Silvia R., et al.
Publicado: (2022)

BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib
por: Godinho, M F E, et al.
Publicado: (2012)

T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression
por: Mustafa, Dana A. M., et al.
Publicado: (2018)

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients
por: Reijm, Esther A., et al.
Publicado: (2016)

Apolipoprotein B mRNA-Editing Catalytic Polypeptide-Like–Induced Protein Changes in Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Throughout Disease Progression
por: Bos, Manouk K., et al.
Publicado: (2022)

High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients
por: Coebergh van den Braak, Robert R. J., et al.
Publicado: (2017)

High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer
por: Jansen, M. P. H. M., et al.
Publicado: (2011)

The Prevalence of CD146 Expression in Breast Cancer Subtypes and Its Relation to Outcome
por: de Kruijff, Ingeborg E., et al.
Publicado: (2018)

Circulating Tumor Cell Enumeration and Characterization in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel
por: de Kruijff, Ingeborg E., et al.
Publicado: (2019)

Integrative whole-genome and transcriptome analysis of HER2-amplified metastatic breast cancer
por: Verschoor, Noortje, et al.
Publicado: (2023)

Improvement of the clinical applicability of the Genomic Grade Index through a qRT-PCR test performed on frozen and formalin-fixed paraffin-embedded tissues
por: Toussaint, Jérôme, et al.
Publicado: (2009)

Co-regulated gene expression of splicing factors as drivers of cancer progression
por: Koedoot, Esmee, et al.
Publicado: (2019)

Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients
por: Liu, Ning Qing, et al.
Publicado: (2016)

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients
por: Beije, Nick, et al.
Publicado: (2017)

4‐protein signature predicting tamoxifen treatment outcome in recurrent breast cancer
por: De Marchi, Tommaso, et al.
Publicado: (2015)

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen
por: Jansen, Maurice P.H.M., et al.
Publicado: (2016)

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer
por: Dalm, Simone U., et al.
Publicado: (2017)

Global proteomic characterization of microdissected estrogen receptor positive breast tumors
por: De Marchi, Tommaso, et al.
Publicado: (2015)

APOBEC3B Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer
por: Sieuwerts, Anieta M., et al.
Publicado: (2019)

Confirmation of a metastasis-specific microRNA signature in primary colon cancer
por: Coebergh van den Braak, Robert R. J, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_vbkqb0qfqvjp4o8mu6f0okh0od