TREM-2 serves as a negative immune regulator through Syk pathway in an IL-10 dependent manner in lung cancer

During infection, triggering receptor expressed on myeloid cells-2 (TREM-2) restrains dendritic cells (DCs) and macrophages (MΦs) phagocytosis, as well as reduces pro-inflammatory cytokines release through DNAX-activation protein 12 (DAP12) signaling. However, the role of TREM-2 signaling in cancer...

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Detalles Bibliográficos
Autores principales: Yao, Yinan, Li, Hequan, Chen, Junjun, Xu, Weiyi, Yang, Guangdie, Bao, Zhang, Xia, Dajing, Lu, Guohua, Hu, Shuwen, Zhou, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045421/
https://www.ncbi.nlm.nih.gov/pubmed/27102437
http://dx.doi.org/10.18632/oncotarget.8813

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