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Notch signaling: its roles and therapeutic potential in hematological malignancies
Notch is a highly conserved signaling system that allows neighboring cells to communicate, thereby controlling their differentiation, proliferation and apoptosis, with the outcome of its activation being highly dependent on signal strength and cell type. As such, there is growing evidence that distu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045435/ https://www.ncbi.nlm.nih.gov/pubmed/26934331 http://dx.doi.org/10.18632/oncotarget.7772 |