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Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin
Resisting cell death is one of the hallmarks of cancer, and represents a common problem resulting in ineffective cancer therapy. To overcome resistance to apoptosis, we designed an antibody-based therapy strategy using Kv10.1 as a target. Kv10.1 is a voltage-gated potassium channel, which has been i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045482/ https://www.ncbi.nlm.nih.gov/pubmed/27350552 http://dx.doi.org/10.1007/s00249-016-1149-7 |