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Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver

The expression of phase-I drug metabolizing enzymes in liver changes dramatically during postnatal liver maturation. Farnesoid X receptor (FXR) is critical for bile acid and lipid homeostasis in liver. However, the role of FXR in regulating ontogeny of phase-I drug metabolizing genes is not clear. H...

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Detalles Bibliográficos
Autores principales:	Peng, Lai, Piekos, Stephanie, Guo, Grace L., Zhong, Xiao-bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045554/ https://www.ncbi.nlm.nih.gov/pubmed/27709014 http://dx.doi.org/10.1016/j.apsb.2016.07.015

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