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RGS14 regulates the lifetime of Gα‐GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells
RGS14 is a multifunctional scaffolding protein possessing two distinct G protein interaction sites including a regulator of G protein signaling (RGS) domain that acts as a GTPase activating protein (GAP) to deactivate Gαi/o‐GTP proteins, and a G protein regulatory (GPR) motif that binds inactive Gαi...
Autores principales: | Brown, Nicole E., Lambert, Nevin A., Hepler, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045935/ https://www.ncbi.nlm.nih.gov/pubmed/27713821 http://dx.doi.org/10.1002/prp2.249 |
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