Cargando…

Th17 Cells Exhibit Antitumor Effects in MDS Possibly through Augmenting Functions of CD8+ T Cells

Th17 cells are a newly found subset of distinct CD4+ Th effector cells' family and are found to play an important role in cancers. Myelodysplastic syndromes (MDS) are a common malignant hematological disease. Here, we showed that both the percentage and the function of Th17 cells were elevated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jing, Yue, Lanzhu, Wang, Huaquan, Liu, Chunyan, Liu, Hui, Tao, Jinglian, Qi, Weiwei, Wang, Yihao, Zhang, Wei, Fu, Rong, Shao, Zonghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046048/ https://www.ncbi.nlm.nih.gov/pubmed/27722177 http://dx.doi.org/10.1155/2016/9404705

Ejemplares similares

Altered follicular helper T cell impaired antibody production in a murine model of myelodysplastic syndromes
por: Jiang, Huijuan, et al.
Publicado: (2017)

Case Report: Sirolimus Alleviates Persistent Cytopenia After CD19 CAR-T-Cell Therapy
por: Xing, Limin, et al.
Publicado: (2021)

Effect of DLK1 on tumorigenesis in CD34(+)CD38(−) bone marrow cells in myelodysplastic syndromes
por: ZHANG, WEI, et al.
Publicado: (2013)

Myeloid dendritic cells in severe aplastic anemia patients exhibit stronger phagocytosis
por: Sun, Yingying, et al.
Publicado: (2021)

Abnormal changes in the quantity and function of osteoblasts cultured in vitro in patients with myelodysplastic syndrome
por: Gao, Shan, et al.
Publicado: (2018)

Detection and Significance of CD4+CD25+CD127dim Regulatory T Cells in Individuals with Severe Aplastic Anemia
por: Qi, Weiwei, et al.
Publicado: (2015)

Upregulated expression of leukocyte immunoglobulin-like receptor A3 in patients with severe aplastic anemia
por: Yu, Hong, et al.
Publicado: (2021)

Abnormal Ferroptosis in Myelodysplastic Syndrome
por: Lv, Qi, et al.
Publicado: (2020)

Successful sirolimus therapy of an aplastic anemia patient with chronic kidney disease: A case report
por: Niu, Haiyue, et al.
Publicado: (2020)

Cofilin‐1 participates in the hyperfunction of myeloid dendritic cells in patients with severe aplastic anaemia
por: Sun, Yingying, et al.
Publicado: (2022)

Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia
por: Zheng, Mengying, et al.
Publicado: (2020)

Abnormal Proteomics Profile of Plasma Reveals the Immunological Pathogenesis of Severe Aplastic Anemia
por: Qi, Weiwei, et al.
Publicado: (2022)

Lower level of IL-35 and its reduced inhibition in Th17 cells in patients with bone marrow mononuclear cells Coombs test-positive hemocytopenia
por: Li, Yi, et al.
Publicado: (2018)

Abnormal expression of histone acetylases in CD8+ T cells of patients with severe aplastic anemia
por: Qi, Weiwei, et al.
Publicado: (2022)

Increased Frequency of Bone Marrow T Follicular Helper Cells in Patients with Immune-Related Pancytopenia
por: Yu, Hong, et al.
Publicado: (2013)

SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia
por: Liu, Yumei, et al.
Publicado: (2022)

Myeloid-derived suppressor cell cytokine secretion as prognostic factor in myelodysplastic syndromes
por: Han, Dong, et al.
Publicado: (2020)

PKM2 Is Required to Activate Myeloid Dendritic Cells from Patients with Severe Aplastic Anemia
por: Liu, Chunyan, et al.
Publicado: (2018)

Impaired Mitophagy of Nucleated Erythroid Cells Leads to Anemia in Patients with Myelodysplastic Syndromes
por: Jiang, Huijuan, et al.
Publicado: (2018)

Piper betle extracts exhibit antitumor activity by augmenting antioxidant potential
por: ALAM, BADRUL, et al.
Publicado: (2015)

Gastrospheres as a Model of Gastric Cancer Stem Cells Skew Th17/Treg Balance toward Antitumor Th17 Cells
por: Rezalotfi, Alaleh, et al.
Publicado: (2020)

Immunological characteristics and effect of cyclosporin in patients with immune thrombocytopenia
por: Wang, Ting, et al.
Publicado: (2021)

Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome
por: Han, Yu, et al.
Publicado: (2016)

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties
por: Prajeeth, Chittappen K., et al.
Publicado: (2017)

RUNX1 mutations contribute to the progression of MDS due to disruption of antitumor cellular defense: a study on patients with lower-risk MDS
por: Kaisrlikova, Monika, et al.
Publicado: (2022)

Single-cell RNA sequencing identifies the properties of myelodysplastic syndrome stem cells
por: Liu, Yumei, et al.
Publicado: (2022)

EUSPEN's 17th International Conference and Exhibition
Publicado: (2017)

Th17 cells and inflammation in neurological disorders: Possible mechanisms of action
por: Shi, Yajun, et al.
Publicado: (2022)

Osteoblast inhibition by chemokine cytokine ligand3 in myeloma-induced bone disease
por: Fu, Rong, et al.
Publicado: (2014)

Paraneoplastic Evans syndrome in a patient with adenocarcinoma of the lung: A case report
por: Yu, Hong, et al.
Publicado: (2016)

ClC5 Decreases the Sensitivity of Multiple Myeloma Cells to Bortezomib via Promoting Prosurvival Autophagy
por: Zhang, Huimin, et al.
Publicado: (2018)

The Role of T Lymphocytes in the Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria
por: Li, Chenyuan, et al.
Publicado: (2021)

P1353: EXPLORING A NOVEL TREATMENT STRATEGY FOR ACQUIRED APLASTIC ANEMIA TARGETING PPAR SIGNALING PATHWAY.
por: Yang, Liping, et al.
Publicado: (2023)

Interleukin 6 exacerbates the progression of warm autoimmune hemolytic anemia by influencing the activity and function of B cells
por: Zhao, Manjun, et al.
Publicado: (2023)

CD8(+) T cells exhaustion induced by myeloid‐derived suppressor cells in myelodysplastic syndromes patients might be through TIM3/Gal‐9 pathway
por: Tao, Jinglian, et al.
Publicado: (2019)

Proliferative activity is disturbed in myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS), and MDS/MPN diseases. Differences between MDS and MDS/MPN
por: Mestrum, Stefan G. C., et al.
Publicado: (2020)

Downregulation of MMP1 in MDS-derived mesenchymal stromal cells reduces the capacity to restrict MDS cell proliferation
por: Zhao, Sida, et al.
Publicado: (2017)

Single-cell RNA sequencing reveals abnormal transcriptome signature of erythroid progenitors in pure red cell aplasia
por: Liu, Yumei, et al.
Publicado: (2023)

Clinical observation of low‐dose combination chemotherapy in refractory/recurrent paroxysmal nocturnal hemoglobinuria patients: A single‐center retrospective analysis
por: Li, Liyan, et al.
Publicado: (2022)

P715: TOX REGULATED CD8+ T LYMPHOCYTES EXHAUSTED IN MYELODYSPLASTIC SYNDROMES PATIENTS THROUGH ACTIVATING AKT/PI3K/MTOR PATHWAY
por: Niu, Haiyue, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q7jf50ljqnj1n8l333h7hqmcfg