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Engagement of distinct epitopes on CD43 induces different co‐stimulatory pathways in human T cells

Co‐receptors, being either co‐stimulatory or co‐inhibitory, play a pivotal role in T‐cell immunity. Several studies have indicated that CD43, one of the abundant T‐cell surface glycoproteins, acts not only as a potent co‐receptor but also as a negative regulator for T‐cell activation. Here we demons...

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Detalles Bibliográficos
Autores principales: Modak, Madhura, Majdic, Otto, Cejka, Petra, Jutz, Sabrina, Puck, Alexander, Gerwien, Jens G., Steinberger, Peter, Zlabinger, Gerhard J., Strobl, Herbert, Stöckl, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046061/
https://www.ncbi.nlm.nih.gov/pubmed/27392084
http://dx.doi.org/10.1111/imm.12642