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Prediction and evaluation of the lipase inhibitory activities of tea polyphenols with 3D-QSAR models
The extraordinary hypolipidemic effects of polyphenolic compounds from tea have been confirmed in our previous study. To gain compounds with more potent activities, using the conformations of the most active compound revealed by molecular docking, a 3D-QSAR pancreatic lipase inhibitor model with goo...
Autores principales: | Li, Yi-Fang, Chang, Yi-Qun, Deng, Jie, Li, Wei-Xi, Jian, Jie, Gao, Jia-Suo, Wan, Xin, Gao, Hao, Kurihara, Hiroshi, Sun, Ping-Hua, He, Rong-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046073/ https://www.ncbi.nlm.nih.gov/pubmed/27694956 http://dx.doi.org/10.1038/srep34387 |
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