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Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention

Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates that reflect lymphoid neogenesis occurring in tissues at sites of inflammation. They are detected in tumors where they orchestrate local and systemic anti-tumor responses. A correlation has been found between high densities of TLS an...

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Detalles Bibliográficos
Autores principales: Sautès-Fridman, Catherine, Lawand, Myriam, Giraldo, Nicolas A., Kaplon, Hélène, Germain, Claire, Fridman, Wolf Herman, Dieu-Nosjean, Marie-Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046074/
https://www.ncbi.nlm.nih.gov/pubmed/27752258
http://dx.doi.org/10.3389/fimmu.2016.00407