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Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study

OBJECTIVE: To evaluate the correlation between constipation and lower urinary tract dysfunction (LUTD) and nocturnal enuresis in a population-based study. MATERIAL AND METHODS: This is a cross-sectional study. The criteria for inclusion were children and adolescents of between 5 and 17 years and who...

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Autores principales: Sampaio, Clara, Sousa, Ariane Sampaio, Fraga, Luis Gustavo A., Veiga, Maria Luiza, Bastos Netto, José Murillo, Barroso, Ubirajara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046079/
https://www.ncbi.nlm.nih.gov/pubmed/27752507
http://dx.doi.org/10.3389/fped.2016.00101
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author Sampaio, Clara
Sousa, Ariane Sampaio
Fraga, Luis Gustavo A.
Veiga, Maria Luiza
Bastos Netto, José Murillo
Barroso, Ubirajara
author_facet Sampaio, Clara
Sousa, Ariane Sampaio
Fraga, Luis Gustavo A.
Veiga, Maria Luiza
Bastos Netto, José Murillo
Barroso, Ubirajara
author_sort Sampaio, Clara
collection PubMed
description OBJECTIVE: To evaluate the correlation between constipation and lower urinary tract dysfunction (LUTD) and nocturnal enuresis in a population-based study. MATERIAL AND METHODS: This is a cross-sectional study. The criteria for inclusion were children and adolescents of between 5 and 17 years and who agreed to sign the informed consent form. The study excluded students with neurological problems or who had documented abnormalities of the urinary tract. To identify the presence and severity of LUTD, we used the Voiding Dysfunction Symptom Score (DVSS). To evaluate the presence of constipation, Rome III questionnaire was used. RESULTS: We interviewed 829 children and adolescents, of which 416 (50.18%) were male. The mean (SD) age was 9.1 (±2.9) years. The overall prevalence of LUTD was 9.1%, predominantly in girls (15 versus 3.1%, p < 0.001). Constipation was found in 9.4% of boys and 12.4% of girls (p = 0.169). Constipated children were 6.8 times more likely to have LUTD than those not constipated (p < 0.001, coefficient and correlation of 0.411). Constipation was found in 8.2% of children without LUTD and in 35.2% of children with LUTD. We performed multivariate analysis to identify urinary symptoms that are independent predictors of the presence of constipation. The presence of infrequent urination (p = 0.004) and holding maneuvers (p < 0.001) were independent predictors. It was noted also noted that constipated children, according to the Rome III criteria, possess a worse DVSS (p < 0.001). Regarding the presence of nocturnal enuresis, 12.6% of children and adolescents had constipation in association with this symptom. However, this relationship was not statistically significant (p = 0.483). CONCLUSION: Constipated children were 6.8 times more likely to have LUTD than those not constipated. Among the urinary symptoms, infrequent voiding and holding maneuvers are independent factors of urinary expressions in constipated children. Children with more severe constipation have more prominent urinary symptoms. The presence of enuresis was not associated with constipation.
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spelling pubmed-50460792016-10-17 Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study Sampaio, Clara Sousa, Ariane Sampaio Fraga, Luis Gustavo A. Veiga, Maria Luiza Bastos Netto, José Murillo Barroso, Ubirajara Front Pediatr Pediatrics OBJECTIVE: To evaluate the correlation between constipation and lower urinary tract dysfunction (LUTD) and nocturnal enuresis in a population-based study. MATERIAL AND METHODS: This is a cross-sectional study. The criteria for inclusion were children and adolescents of between 5 and 17 years and who agreed to sign the informed consent form. The study excluded students with neurological problems or who had documented abnormalities of the urinary tract. To identify the presence and severity of LUTD, we used the Voiding Dysfunction Symptom Score (DVSS). To evaluate the presence of constipation, Rome III questionnaire was used. RESULTS: We interviewed 829 children and adolescents, of which 416 (50.18%) were male. The mean (SD) age was 9.1 (±2.9) years. The overall prevalence of LUTD was 9.1%, predominantly in girls (15 versus 3.1%, p < 0.001). Constipation was found in 9.4% of boys and 12.4% of girls (p = 0.169). Constipated children were 6.8 times more likely to have LUTD than those not constipated (p < 0.001, coefficient and correlation of 0.411). Constipation was found in 8.2% of children without LUTD and in 35.2% of children with LUTD. We performed multivariate analysis to identify urinary symptoms that are independent predictors of the presence of constipation. The presence of infrequent urination (p = 0.004) and holding maneuvers (p < 0.001) were independent predictors. It was noted also noted that constipated children, according to the Rome III criteria, possess a worse DVSS (p < 0.001). Regarding the presence of nocturnal enuresis, 12.6% of children and adolescents had constipation in association with this symptom. However, this relationship was not statistically significant (p = 0.483). CONCLUSION: Constipated children were 6.8 times more likely to have LUTD than those not constipated. Among the urinary symptoms, infrequent voiding and holding maneuvers are independent factors of urinary expressions in constipated children. Children with more severe constipation have more prominent urinary symptoms. The presence of enuresis was not associated with constipation. Frontiers Media S.A. 2016-10-03 /pmc/articles/PMC5046079/ /pubmed/27752507 http://dx.doi.org/10.3389/fped.2016.00101 Text en Copyright © 2016 Sampaio, Sousa, Fraga, Veiga, Bastos Netto and Barroso. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Sampaio, Clara
Sousa, Ariane Sampaio
Fraga, Luis Gustavo A.
Veiga, Maria Luiza
Bastos Netto, José Murillo
Barroso, Ubirajara
Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title_full Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title_fullStr Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title_full_unstemmed Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title_short Constipation and Lower Urinary Tract Dysfunction in Children and Adolescents: A Population-Based Study
title_sort constipation and lower urinary tract dysfunction in children and adolescents: a population-based study
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046079/
https://www.ncbi.nlm.nih.gov/pubmed/27752507
http://dx.doi.org/10.3389/fped.2016.00101
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