Cargando…

Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids

Phenylalanine hydroxylase (PAH) is a key tyrosine-biosynthetic enzyme involved in neurological and melanin-associated physiological processes. Despite extensive investigations in holometabolous insects, a PAH contribution to insect embryonic development has never been demonstrated. Here, we have cha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simonet, Pierre, Gaget, Karen, Parisot, Nicolas, Duport, Gabrielle, Rey, Marjolaine, Febvay, Gérard, Charles, Hubert, Callaerts, Patrick, Colella, Stefano, Calevro, Federica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046115/ https://www.ncbi.nlm.nih.gov/pubmed/27694983 http://dx.doi.org/10.1038/srep34321

Ejemplares similares

Bacteriocyte Reprogramming to Cope With Nutritional Stress in a Phloem Sap Feeding Hemipteran, the Pea Aphid Acyrthosiphon pisum
por: Colella, Stefano, et al.
Publicado: (2018)

Bacteriocyte cell death in the pea aphid/Buchnera symbiotic system
por: Simonet, Pierre, et al.
Publicado: (2018)

Tyrosine pathway regulation is host-mediated in the pea aphid symbiosis during late embryonic and early larval development
por: Rabatel, Andréane, et al.
Publicado: (2013)

Bacteriocyte plasticity in pea aphids facing amino acid stress or starvation during development
por: Ribeiro Lopes, Mélanie, et al.
Publicado: (2022)

Direct flow cytometry measurements reveal a fine-tuning of symbiotic cell dynamics according to the host developmental needs in aphid symbiosis
por: Simonet, Pierre, et al.
Publicado: (2016)

Multimodal dynamic response of the Buchnera aphidicola pLeu plasmid to variations in leucine demand of its host, the pea aphid Acyrthosiphon pisum
por: Viñuelas, José, et al.
Publicado: (2011)

Evolutionary novelty in the apoptotic pathway of aphids
por: Ribeiro Lopes, Mélanie, et al.
Publicado: (2020)

Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily
por: Loth, Karine, et al.
Publicado: (2022)

Compartmentalized into Bacteriocytes but Highly Invasive: the Puzzling Case of the Co-Obligate Symbiont Serratia symbiotica in the Aphid Periphyllus lyropictus
por: Renoz, François, et al.
Publicado: (2022)

Gene Expression Analysis of Parthenogenetic Embryonic Development of the Pea Aphid, Acyrthosiphon pisum, Suggests That Aphid Parthenogenesis Evolved from Meiotic Oogenesis
por: Srinivasan, Dayalan G., et al.
Publicado: (2014)

Post-reproductive parthenogenetic pea aphids (Acyrthosiphon pisum) are visually identifiable and disproportionately positioned distally to clonal colonies
por: Saberski, Erik T., et al.
Publicado: (2016)

Structure and dynamics of the operon map of Buchnera aphidicola sp. strain APS
por: Brinza, Lilia, et al.
Publicado: (2010)

Effects of RNAi-based silencing of chitin synthase gene on moulting and fecundity in pea aphids (Acyrthosiphon pisum)
por: Ye, Chao, et al.
Publicado: (2019)

Heat shock protein 83 plays pleiotropic roles in embryogenesis, longevity, and fecundity of the pea aphid Acyrthosiphon pisum
por: Will, Torsten, et al.
Publicado: (2016)

Phenylalanine Binding Is Linked to Dimerization of the Regulatory Domain of Phenylalanine Hydroxylase
por: Zhang, Shengnan, et al.
Publicado: (2014)

A Genomic Reappraisal of Symbiotic Function in the Aphid/Buchnera Symbiosis: Reduced Transporter Sets and Variable Membrane Organisations
por: Charles, Hubert, et al.
Publicado: (2011)

Widespread failure to complete meiosis does not impair fecundity in parthenogenetic whiptail lizards
por: Newton, Aracely A., et al.
Publicado: (2016)

Phenylalanine Hydroxylase Misfolding and Pharmacological Chaperones
por: Underhaug, Jarl, et al.
Publicado: (2012)

Activation of Phenylalanine Hydroxylase by Phenylalanine Does Not Require Binding in the Active Site
por: Roberts, Kenneth M., et al.
Publicado: (2014)

Nicotinamide Inhibits Aphid Fecundity and Impacts Survival
por: Sattar, Sampurna, et al.
Publicado: (2019)

ArthropodaCyc: a CycADS powered collection of BioCyc databases to analyse and compare metabolism of arthropods
por: Baa-Puyoulet, Patrice, et al.
Publicado: (2016)

Recommendations for the nutrition management of phenylalanine hydroxylase deficiency
por: Singh, Rani H., et al.
Publicado: (2014)

The Di-Symbiotic Systems in the Aphids Sipha maydis and Periphyllus lyropictus Provide a Contrasting Picture of Recent Co-Obligate Nutritional Endosymbiosis in Aphids
por: Renoz, François, et al.
Publicado: (2022)

Masculinization of the X Chromosome in the Pea Aphid
por: Jaquiéry, Julie, et al.
Publicado: (2013)

Feeding, fecundity and lifespan in female Drosophila melanogaster
por: Barnes, Andrew I, et al.
Publicado: (2008)

Structural Features of the Regulatory ACT Domain of Phenylalanine Hydroxylase
por: Carluccio, Carla, et al.
Publicado: (2013)

Mutations of the phenylalanine hydroxylase gene in Iranian patients with phenylketonuria
por: Biglari, Alireza, et al.
Publicado: (2015)

Dynamic Regulation of Phenylalanine Hydroxylase by Simulated Redox Manipulation
por: Fuchs, Julian E., et al.
Publicado: (2012)

Genotypes of patients with phenylalanine hydroxylase deficiency in the Wisconsin Amish
por: Schwoerer, Jessica Scott, et al.
Publicado: (2018)

Characterization of phenylalanine hydroxylase gene variants and analysis of genotype–phenotype correlation in patients with phenylalanine hydroxylase deficiency from Fujian Province, Southeastern China
por: Zhou, Jinfu, et al.
Publicado: (2022)

Spatio-temporal patterns of ovarian development and VgR gene silencing reduced fecundity in parthenogenetic Artemia
por: Duan, Hu, et al.
Publicado: (2023)

Genome Sequence of the Pea Aphid Acyrthosiphon pisum
Publicado: (2010)

EMS Mutagenesis in the Pea Aphid Acyrthosiphon pisum
por: Tagu, Denis, et al.
Publicado: (2014)

Genetic Control of Contagious Asexuality in the Pea Aphid
por: Jaquiéry, Julie, et al.
Publicado: (2014)

Mutations of the phenylalanine hydroxylase gene in patients with phenylketonuria in Shanxi, China
por: Zhou, Yong-An, et al.
Publicado: (2012)

Phenylalanine Hydroxylase Deficiency and Citrin Deficiency in a Chinese Infant
por: Ye, Jun, et al.
Publicado: (2015)

Stabilization of tryptophan hydroxylase 2 by l‐phenylalanine‐induced dimerization
por: Tidemand, Kasper D., et al.
Publicado: (2016)

Mutation analysis of Phenylalanine hydroxylase gene in Iranian patients with Phenylketonuria
por: Rastegar Moghadam, Mahsa, et al.
Publicado: (2018)

Structural and Functional Impact of Seven Missense Variants of Phenylalanine Hydroxylase
por: Pecimonova, Martina, et al.
Publicado: (2019)

Optical Coherence Tomography to Assess Neurodegeneration in Phenylalanine Hydroxylase Deficiency
por: Lotz-Havla, Amelie S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ja7i13ike798oupq53i2j62o88