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Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids
Phenylalanine hydroxylase (PAH) is a key tyrosine-biosynthetic enzyme involved in neurological and melanin-associated physiological processes. Despite extensive investigations in holometabolous insects, a PAH contribution to insect embryonic development has never been demonstrated. Here, we have cha...
Autores principales: | Simonet, Pierre, Gaget, Karen, Parisot, Nicolas, Duport, Gabrielle, Rey, Marjolaine, Febvay, Gérard, Charles, Hubert, Callaerts, Patrick, Colella, Stefano, Calevro, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046115/ https://www.ncbi.nlm.nih.gov/pubmed/27694983 http://dx.doi.org/10.1038/srep34321 |
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