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Disruption of phenylalanine hydroxylase reduces adult lifespan and fecundity, and impairs embryonic development in parthenogenetic pea aphids

Phenylalanine hydroxylase (PAH) is a key tyrosine-biosynthetic enzyme involved in neurological and melanin-associated physiological processes. Despite extensive investigations in holometabolous insects, a PAH contribution to insect embryonic development has never been demonstrated. Here, we have cha...

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Detalles Bibliográficos
Autores principales: Simonet, Pierre, Gaget, Karen, Parisot, Nicolas, Duport, Gabrielle, Rey, Marjolaine, Febvay, Gérard, Charles, Hubert, Callaerts, Patrick, Colella, Stefano, Calevro, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046115/
https://www.ncbi.nlm.nih.gov/pubmed/27694983
http://dx.doi.org/10.1038/srep34321

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