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Time-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats

Lipopolysaccharide (LPS) can lead to uncontrollable cytokine production and eventually cause fatal sepsis syndrome. Individual toxicity difference of LPS has been widely reported. In our study we observed that two thirds of the rats (24/36) died at a given dose of LPS, while the rest (12/36) survive...

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Detalles Bibliográficos
Autores principales: Dai, Die, Gao, Yiqiao, Chen, Jiaqing, Huang, Yin, Zhang, Zunjian, Xu, Fengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046119/
https://www.ncbi.nlm.nih.gov/pubmed/27695004
http://dx.doi.org/10.1038/srep34136