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Transforming growth factor β as regulator of cancer stemness and metastasis

Key elements of cancer progression towards metastasis are the biological actions of cancer stem cells and stromal cells in the tumour microenvironment. Cross-communication between tumour and stromal cells is mediated by secreted cytokines, one of which, the transforming growth factor β (TGFβ), regul...

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Detalles Bibliográficos
Autores principales: Bellomo, Claudia, Caja, Laia, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046208/
https://www.ncbi.nlm.nih.gov/pubmed/27537386
http://dx.doi.org/10.1038/bjc.2016.255