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Delayed DNA double-strand break repair following platin-based chemotherapy predicts treatment response in head and neck squamous cell carcinoma

INTRODUCTION: The aim of this study was to investigate if defective repair of DNA double-strand break (DSB) in head and neck squamous cell carcinoma (HNSCC) could be used as an early predictor of treatment response. METHODS: Tumour biopsy 24–36 h following induction chemotherapy (IC) and pre-treatme...

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Detalles Bibliográficos
Autores principales:	Bhide, S A, Thway, K, Lee, J, Wong, K, Clarke, P, Newbold, K L, Nutting, C M, Harrington, K J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046213/ https://www.ncbi.nlm.nih.gov/pubmed/27584664 http://dx.doi.org/10.1038/bjc.2016.266

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