FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes

Mitochondrial uncoupling proteins (UCPs) are inducible and play an important role in metabolic and redox homeostasis. Recent studies have suggested that FoxO1 controls mitochondrial biogenesis and morphology, but it remains largely unknown how FoxO1 may regulate mitochondrial UCPs. Here we show that...

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Detalles Bibliográficos
Autores principales: Liu, Longhua, Tao, Zhipeng, Zheng, Louise D, Brooke, Joseph P, Smith, Cayleen M, Liu, Dongmin, Long, Yun Chau, Cheng, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046220/
https://www.ncbi.nlm.nih.gov/pubmed/27777789
http://dx.doi.org/10.1038/cddiscovery.2016.66

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