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Importance of rare gene copy number alterations for personalized tumor characterization and survival analysis
It has proven exceedingly difficult to ascertain rare copy number alterations (CNAs) that may have strong effects in individual tumors. We show that a regulatory network inferred from gene expression and gene copy number data of 768 human cancer cell lines can be used to quantify the impact of patie...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046221/ https://www.ncbi.nlm.nih.gov/pubmed/27716417 http://dx.doi.org/10.1186/s13059-016-1058-1 |