Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study

Creatinine is widely used as an indirect marker of renal function. However, interfering factors such as diet, exercise and problems with the assay can generate false results and misinterpretation of real kidney function. In this article, we report the dietary effects on serum creatinine during a pha...

Descripción completa

Detalles Bibliográficos
Autores principales: Pimenta, Eduardo, Jensen, Markus, Jung, David, Schaumann, Frank, Boxnick, Stefanie, Truebel, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047024/
https://www.ncbi.nlm.nih.gov/pubmed/27738487
http://dx.doi.org/10.14740/jocmr2738w
_version_ 1782457381976801280
author Pimenta, Eduardo
Jensen, Markus
Jung, David
Schaumann, Frank
Boxnick, Stefanie
Truebel, Hubert
author_facet Pimenta, Eduardo
Jensen, Markus
Jung, David
Schaumann, Frank
Boxnick, Stefanie
Truebel, Hubert
author_sort Pimenta, Eduardo
collection PubMed
description Creatinine is widely used as an indirect marker of renal function. However, interfering factors such as diet, exercise and problems with the assay can generate false results and misinterpretation of real kidney function. In this article, we report the dietary effects on serum creatinine during a phase I single dose escalation study and discuss the reasons why serum creatinine should be measured under fasting conditions.
format Online
Article
Text
id pubmed-5047024
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elmer Press
record_format MEDLINE/PubMed
spelling pubmed-50470242016-10-13 Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study Pimenta, Eduardo Jensen, Markus Jung, David Schaumann, Frank Boxnick, Stefanie Truebel, Hubert J Clin Med Res Case Report Creatinine is widely used as an indirect marker of renal function. However, interfering factors such as diet, exercise and problems with the assay can generate false results and misinterpretation of real kidney function. In this article, we report the dietary effects on serum creatinine during a phase I single dose escalation study and discuss the reasons why serum creatinine should be measured under fasting conditions. Elmer Press 2016-11 2016-09-29 /pmc/articles/PMC5047024/ /pubmed/27738487 http://dx.doi.org/10.14740/jocmr2738w Text en Copyright 2016, Pimenta et al. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Pimenta, Eduardo
Jensen, Markus
Jung, David
Schaumann, Frank
Boxnick, Stefanie
Truebel, Hubert
Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title_full Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title_fullStr Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title_full_unstemmed Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title_short Effect of Diet on Serum Creatinine in Healthy Subjects During a Phase I Study
title_sort effect of diet on serum creatinine in healthy subjects during a phase i study
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047024/
https://www.ncbi.nlm.nih.gov/pubmed/27738487
http://dx.doi.org/10.14740/jocmr2738w
work_keys_str_mv AT pimentaeduardo effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy
AT jensenmarkus effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy
AT jungdavid effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy
AT schaumannfrank effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy
AT boxnickstefanie effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy
AT truebelhubert effectofdietonserumcreatinineinhealthysubjectsduringaphaseistudy

Ejemplares similares