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Characterization of a functional C3A liver spheroid model

More predictive in vitro liver models are a critical requirement for preclinical screening of compounds demonstrating hepatotoxic liability. 3D liver spheroids have been shown to have an enhanced functional lifespan compared to 2D monocultures; however a detailed characterisation of spatiotemporal f...

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Detalles Bibliográficos
Autores principales: Gaskell, Harriet, Sharma, Parveen, Colley, Helen E., Murdoch, Craig, Williams, Dominic P., Webb, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047049/
https://www.ncbi.nlm.nih.gov/pubmed/27746894
http://dx.doi.org/10.1039/c6tx00101g