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Characterization of a functional C3A liver spheroid model

More predictive in vitro liver models are a critical requirement for preclinical screening of compounds demonstrating hepatotoxic liability. 3D liver spheroids have been shown to have an enhanced functional lifespan compared to 2D monocultures; however a detailed characterisation of spatiotemporal f...

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Detalles Bibliográficos
Autores principales:	Gaskell, Harriet, Sharma, Parveen, Colley, Helen E., Murdoch, Craig, Williams, Dominic P., Webb, Steven D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047049/ https://www.ncbi.nlm.nih.gov/pubmed/27746894 http://dx.doi.org/10.1039/c6tx00101g

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