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Successful Treatment of Disseminated Anncaliia algerae Microsporidial Infection With Combination Fumagillin and Albendazole

Anncaliia algerae myositis is a life-threatening, emerging microsporidiosis among immunocompromised hosts. We report a case of disseminated A algerae infection in a man previously treated with alemtuzumab. Due to failure of albendazole-based therapy, fumagillin was added as a novel approach to manag...

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Detalles Bibliográficos
Autores principales: Boileau, Mélissa, Ferreira, José, Ahmad, Imran, Lavallée, Christian, Qvarnstrom, Yvonne, Dufresne, Simon F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047403/
https://www.ncbi.nlm.nih.gov/pubmed/27704013
http://dx.doi.org/10.1093/ofid/ofw158
Descripción
Sumario:Anncaliia algerae myositis is a life-threatening, emerging microsporidiosis among immunocompromised hosts. We report a case of disseminated A algerae infection in a man previously treated with alemtuzumab. Due to failure of albendazole-based therapy, fumagillin was added as a novel approach to management, with a good clinical response and patient survival.