Diagnosis of Capnocytophaga canimorsus Sepsis by Whole-Genome Next-Generation Sequencing

We report the case of a 60-year-old man with septic shock due to Capnocytophaga canimorsus that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay. This technology shows great promise in identifying fastidious pathogens, and, if validated, it has profound implications...

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Detalles Bibliográficos
Autores principales: Abril, Maria K., Barnett, Adam S., Wegermann, Kara, Fountain, Eric, Strand, Andrew, Heyman, Benjamin M., Blough, Britton A., Swaminathan, Aparna C., Sharma-Kuinkel, Batu, Ruffin, Felicia, Alexander, Barbara D., McCall, Chad M., Costa, Sylvia F., Arcasoy, Murat O., Hong, David K., Blauwkamp, Timothy A., Kertesz, Michael, Fowler, Vance G., Kraft, Bryan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047422/
https://www.ncbi.nlm.nih.gov/pubmed/27704003
http://dx.doi.org/10.1093/ofid/ofw144
Descripción
Sumario:We report the case of a 60-year-old man with septic shock due to Capnocytophaga canimorsus that was diagnosed in 24 hours by a novel whole-genome next-generation sequencing assay. This technology shows great promise in identifying fastidious pathogens, and, if validated, it has profound implications for infectious disease diagnosis.

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