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Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography

A maximum-likelihood reconstruction technique for X-ray Talbot-Lau tomography is presented. This technique allows the iterative simultaneous reconstruction of discrete distributions of absorption coefficient, refractive index and a dark-field scattering coefficient. This technique avoids prior phase...

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Detalles Bibliográficos
Autores principales: Ritter, André, Anton, Gisela, Weber, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047447/
https://www.ncbi.nlm.nih.gov/pubmed/27695126
http://dx.doi.org/10.1371/journal.pone.0163016
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author Ritter, André
Anton, Gisela
Weber, Thomas
author_facet Ritter, André
Anton, Gisela
Weber, Thomas
author_sort Ritter, André
collection PubMed
description A maximum-likelihood reconstruction technique for X-ray Talbot-Lau tomography is presented. This technique allows the iterative simultaneous reconstruction of discrete distributions of absorption coefficient, refractive index and a dark-field scattering coefficient. This technique avoids prior phase retrieval in the tomographic projection images and thus in principle allows reconstruction from tomographic data with less than three phase steps per projection. A numerical phantom is defined which is used to evaluate convergence of the technique with regard to photon statistics and with regard to the number of projection angles and phase steps used. It is shown that the use of a random phase sampling pattern allows the reconstruction even for the extreme case of only one single phase step per projection. The technique is successfully applied to measured tomographic data of a mouse. In future, this reconstruction technique might also be used to implement enhanced imaging models for X-ray Talbot-Lau tomography. These enhancements might be suited to correct for example beam hardening and dispersion artifacts and improve overall image quality of X-ray Talbot-Lau tomography.
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spelling pubmed-50474472016-10-27 Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography Ritter, André Anton, Gisela Weber, Thomas PLoS One Research Article A maximum-likelihood reconstruction technique for X-ray Talbot-Lau tomography is presented. This technique allows the iterative simultaneous reconstruction of discrete distributions of absorption coefficient, refractive index and a dark-field scattering coefficient. This technique avoids prior phase retrieval in the tomographic projection images and thus in principle allows reconstruction from tomographic data with less than three phase steps per projection. A numerical phantom is defined which is used to evaluate convergence of the technique with regard to photon statistics and with regard to the number of projection angles and phase steps used. It is shown that the use of a random phase sampling pattern allows the reconstruction even for the extreme case of only one single phase step per projection. The technique is successfully applied to measured tomographic data of a mouse. In future, this reconstruction technique might also be used to implement enhanced imaging models for X-ray Talbot-Lau tomography. These enhancements might be suited to correct for example beam hardening and dispersion artifacts and improve overall image quality of X-ray Talbot-Lau tomography. Public Library of Science 2016-10-03 /pmc/articles/PMC5047447/ /pubmed/27695126 http://dx.doi.org/10.1371/journal.pone.0163016 Text en © 2016 Ritter et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ritter, André
Anton, Gisela
Weber, Thomas
Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title_full Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title_fullStr Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title_full_unstemmed Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title_short Simultaneous Maximum-Likelihood Reconstruction of Absorption Coefficient, Refractive Index and Dark-Field Scattering Coefficient in X-Ray Talbot-Lau Tomography
title_sort simultaneous maximum-likelihood reconstruction of absorption coefficient, refractive index and dark-field scattering coefficient in x-ray talbot-lau tomography
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047447/
https://www.ncbi.nlm.nih.gov/pubmed/27695126
http://dx.doi.org/10.1371/journal.pone.0163016
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