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Enhancing Predicted Efficacy of Tumor Treating Fields Therapy of Glioblastoma Using Targeted Surgical Craniectomy: A Computer Modeling Study
OBJECTIVE: The present work proposes a new clinical approach to TTFields therapy of glioblastoma. The approach combines targeted surgical skull removal (craniectomy) with TTFields therapy to enhance the induced electrical field in the underlying tumor tissue. Using computer simulations, we explore t...
Autores principales: | Korshoej, Anders Rosendal, Saturnino, Guilherme Bicalho, Rasmussen, Line Kirkegaard, von Oettingen, Gorm, Sørensen, Jens Christian Hedemann, Thielscher, Axel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047456/ https://www.ncbi.nlm.nih.gov/pubmed/27695068 http://dx.doi.org/10.1371/journal.pone.0164051 |
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