Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation

The ribosomal RNA (rRNA) gene encodes rRNA for protein synthesis. Aberrant expression of the rRNA gene has been generally observed in tumor cells and levels of its promoter methylation as an epigenetic regulator affect rRNA gene transcription. The possible relationship between expression and promote...

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Detalles Bibliográficos
Autores principales: Zhou, Hong, Wang, Yapei, Lv, Qiongying, Zhang, Juan, Wang, Qing, Gao, Fei, Hou, Haoli, Zhang, Hao, Zhang, Wei, Li, Lijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047480/
https://www.ncbi.nlm.nih.gov/pubmed/27695092
http://dx.doi.org/10.1371/journal.pone.0163340

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