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GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes

Toll-like receptors (TLR) are crucial sensors of microbial agents such as bacterial or viral compounds. These receptors constitute key players in the induction of inflammation, e.g. in septic or chronic inflammatory diseases. Colony-stimulating factors (CSFs) such as granulocyte-macrophage-CSF (GM-C...

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Detalles Bibliográficos
Autores principales:	Sadeghi, Kambis, Wisgrill, Lukas, Wessely, Isabelle, Diesner, Susanne C., Schüller, Simone, Dürr, Celia, Heinle, Armando, Sachet, Monika, Pollak, Arnold, Förster-Waldl, Elisabeth, Spittler, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047522/ https://www.ncbi.nlm.nih.gov/pubmed/27695085 http://dx.doi.org/10.1371/journal.pone.0162667

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