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Autophagy resolves early retinal inflammation in Igf1-deficient mice

Insulin-like growth factor-1 (IGF-1) is a growth factor with differentiating, anti-apoptotic and metabolic functions in the periphery, and anti-inflammatory properties in the nervous system. Mice that have mutations in the Igf1 gene, rendering the gene product inactive (Igf1(−/−)), present with age-...

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Detalles Bibliográficos
Autores principales: Arroba, Ana I., Rodríguez-de la Rosa, Lourdes, Murillo-Cuesta, Silvia, Vaquero-Villanueva, Laura, Hurlé, Juan M., Varela-Nieto, Isabel, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047685/
https://www.ncbi.nlm.nih.gov/pubmed/27483352
http://dx.doi.org/10.1242/dmm.026344

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