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Regulation of the Abundance of Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2

The switch between latency and the lytic cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown. Our earlier studies have demonstrated that a pro...

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Detalles Bibliográficos
Autores principales: Chang, Tzu-Hsuan, Wang, Shie-Shan, Chen, Lee-Wen, Shih, Ying-Ju, Chang, Li-Kwan, Liu, Shih-Tung, Chang, Pey-Jium
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047794/
https://www.ncbi.nlm.nih.gov/pubmed/27698494
http://dx.doi.org/10.1371/journal.ppat.1005918

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