Guidelines to PET measurements of the target occupancy in the brain for drug development

This guideline summarizes the current view of the European Association of Nuclear Medicine Drug Development Committee. The purpose of this guideline is to guarantee a high standard of PET studies that are aimed at measuring target occupancy in the brain within the framework of development programs o...

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Detalles Bibliográficos
Autores principales: Takano, Akihiro, Varrone, Andrea, Gulyás, Balázs, Salvadori, Piero, Gee, Antony, Windhorst, Albert, Vercouillie, Johnny, Bormans, Guy, Lammertsma, Adriaan A., Halldin, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Guidelines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047931/
https://www.ncbi.nlm.nih.gov/pubmed/27514528
http://dx.doi.org/10.1007/s00259-016-3476-4
Descripción
Sumario:This guideline summarizes the current view of the European Association of Nuclear Medicine Drug Development Committee. The purpose of this guideline is to guarantee a high standard of PET studies that are aimed at measuring target occupancy in the brain within the framework of development programs of drugs that act within the central nervous system (CNS drugs). This guideline is intended to present information specifically adapted to European practice. The information provided should be applied within the context of local conditions and regulations.

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